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Improving Health


Changing patients’ lives

Medicines continue to transform the lives of patients across multiple disease areas. Take HIV, for example: antiretroviral medications have made HIV, a disease that was once invariably fatal, into a manageable chronic condition for many [14]. For people living with Hepatitis C, 95% can now be cured with a 12-week course of medicine – an achievement that would have been impossible without game-changing advances in medical science [15]. Take breast cancer where new treatments have resulted in a gain of nearly 1.2 million healthy life years between 2007 and 2017 [16]. What is impossible to quantify is the value of mums, daughters, grandmothers, friends having more time with the ones they love. That is #MoreThanMedicine.


Preventing illness

Vaccines and medicines are improving health not only by treating patients but by preventing illness in first place. It is more than avoiding clinical symptoms and reducing the need for medical care. Prevention provides opportunities to flourish, keeping children in school, ensuring adults can play an active role in their communities and contribute to the economy. It means avoiding the burden on individuals and families that are associated with stroke or the complications of diabetes. And it helps ensure a more sustainable future for health and care systems by avoiding or slowing the progression of chronic illness.

 

Impact of preventing illness:
  • Saving lives and preventing disability: Between 2001 and 2020, vaccines averted an estimated 20 million deaths, 500 million cases of illness, and 9 million cases of long-term disability globally [1] [2]
  • Healthier children: Vaccinated children attend school more regularly than those who have not been vaccinated; they have better cognitive performance and obtain higher grades [3].
  • Reduced hospitalisation: In Spain, hospitalisations due to chickenpox decreased by 78% after routine vaccination of 15–18-month-old infants between 2006 and 2010 [4].
  • Less disease: In Italy, introduction of routine vaccination against hepatitis B virus (HBV) led to an 82% decline in the incidence of HBV from 1991 to 2010 [5].
  • HIV: Thanks to successful therapies, the number of AIDS deaths worldwide has more than halved in the last 20 years [6].
  • Pandemic response: Pharmaceutical companies have developed vaccines against COVID-19 to reduce the risk of people being hospitalised or dying. Two years after COVID-19 was declared to be a pandemic, more than 12 billion doses [7] had been administered globally, averting at least 20 million deaths [8] [9].
  • Ending polio: Since 1988, polio cases have decreased by over 99% [10]. An estimated 18 million people can walk today who would have otherwise been paralysed, and 1.5 million childhood deaths have been averted through immunisation activities [11].
  • Controlling complications: The discovery of insulin has saved millions of lives and prevented complications, including kidney disease, heart disease and problems with vision, oral health and feet [12].
  • Healthier hearts: Statins, cholesterol-busting medications taken by millions of people in Europe, are proven to reduce the risk of heart attack and stroke, including for those who have already suffered a cardiac event [13].


Antimicrobial Resistance: a societal challenge

Antimicrobials have improved the lives of millions of people, making healthcare safer and more efficient. However, antimicrobial resistance (AMR) poses a real and urgent threat to individuals and health systems.

Developing the next generation of antibiotics is a priority for society. Industry is playing its part in rising to the challenge. The pharmaceutical industry, leading global philanthropies and development banks have formed the AMR Action Fund – dedicating around €1 billion to help respond to the AMR threat. The Fund aims to bring 2-4 new antibiotics to market this decade.


Working with Health Systems

The pharmaceutical industry delivers #MoreThanMedicine to health systems. Companies are at the forefront of advances in digital health, new ways to introduce technologies into health systems and novel partnerships that bring innovation to how care is delivered enabling patients to monitor their disease and take action when needed. They develop patient support tools like reminders for patients to take their medicine, simpler or automated measurements of markers of a patient’s disease that can be shared live with their doctor.

We will continue to share expertise and knowhow, taking a collaborative approach to co-create solutions to the common challenges we face as a society.

From the novel use of digital tools to identify familial hypercholesterolemia (FH) patients in Sweden to improving care and outcomes for respiratory patients in the UK, there are a series of case studies on industry-health system collaborative initiatives to advance patient care and improve outcomes for patients and the health systems.


Case studies
Pioneering the use of innovative digital health tools in Sweden
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It is estimated that less than 5% of people in Sweden with familial hypercholesterolemia (FH) have been diagnosed with the condition. In response, Amgen formed a partnership with Health Solutions and the Karolinska University Hospital and together developed FHabian, a secure web-based platform for people diagnosed with FH to create a virtual family tree and invite relatives to screening.

Following a successful pilot, it is now in routine use at the Karolinska University Hospital where experts estimate it will allow them to find and diagnose half of all people with FH in the Stockholm region within three years. This corresponds to about 3,700 patients currently undiagnosed.2

Fhabian was shortlisted for the Svea prize in 2021, an award in Sweden which recognises innovative solutions for eHealth.


Partnership to improve outcomes for respiratory patients in the UK
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People with respiratory illnesses, such as asthma and COPD, sometimes need care from several specialists at primary care and hospital level. Connecting these services can be a challenge for patients navigating the health system. Boehringer Ingelheim developed a partnership aimed to improve care and outcomes for respiratory patients in Oxfordshire, UK. Working with local healthcare providers and bringing together their collective skills and expertise, they piloted a multidisciplinary integrated respiratory team that coordinated service provision around the needs of patients.

This partnership approach led to timely, coordinated care closer to home for respiratory patients in the area which showed potential to reduce system costs and resulted in improved patient experience and outcomes. The project won a Health Service Journal (HSJ) partnership award in 2021.

Mapping the experiences of patients with Axial Spondyloarthritis
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Connecting healthcare stakeholders to advance patient care is a priority for pharmaceutical companies. Building relationships between the academic, health professional, industry and patient communities can deliver breakthroughs that are not possible when one actor works alone. The Connecting Healthcare Awards celebrate multi-stakeholder collaboration sharing inspiring examples from dozens of projects across Europe[17].

The International Map of Axial Spondyloarthritis (IMAS) was a worthy winner of the overall prize in the Connecting Healthcare Awards. This initiative gathered real-world insights from over 4,000 participants, capturing patient experiences in a way rarely reflected in clinical studies. The findings triggered discussions with patients and rheumatologists worldwide to inform clinical decision-making, shorten diagnostic delay and ensure patients receive optimal care. In addition to publishing 48 scientific abstracts and congress presentations, the project was brought to life through an interactive artistic sculpture on display at a premier rheumatology congress.

 




Powering up Europe’s health systems

EFPIA takes a long-term view of advancing health and is stepping up to its responsibilities in meeting the challenges of our time: rising rates of chronic diseases, antimicrobial resistance and climate change. To support the renewed political and public prioritisation of health, we have set out five priorities for investing in European healthcare.

Our shared goal must be to POWER up our health system, focusing on:

POWERing up means embracing the transformational tools we need – namely digitalisation and innovation that generates value for patients, health systems and society as a whole. By proposing concrete and detailed solutions, we are demonstrating our willingness to work with others to improve our health systems. We are delivering #MoreThanMedicine.


Response to emergencies

Europe has continued to count the devastating human and economic cost of the COVID-19 pandemic and, in solidarity with people across Europe, we have expressed our sorrow at the suffering caused by Russia’s invasion of Ukraine. The response from our industry was an unprecedented collaborative effort to find vaccines and treatments that could protect citizens against the coronavirus and in Ukraine, companies have come together to donate around 30 million doses of vital medicines, again delivering #MoreThanMedicine.

 


References

[1] •-2-VE-public-health-impact-infographic.pdf (vaccineseurope.eu)

[2] Immunization (who.int)

[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371956

[4] https://www.vaccineseurope.eu/news/articles/realising-the-full-value-of-vaccination

[5] Boccalini 2013 Economic analysis of the first 20 years of universal hepatitis B vaccination program in Italy Human Vaccines & Immunotherapies http://dx.doi.org/10.4161/hv.23827

[6] UNAIDS (2021), Factsheet World AIDS Day 2021.

[7] Coronavirus (COVID-19) Vaccinations - Our World in Data

[8] Global impact of the first year of COVID-19 vaccination: a mathematical modelling study - The Lancet Infectious Diseases

[9] https://ec.europa.eu/info/live-work-travel-eu/coronavirus-response/safe-covid-19-vaccines-europeans_en;

[10] Poliomyelitis (who.int)

[11] Global Health - Newsroom - Polio (cdc.gov)

[12] What’s next in diabetes care - 100 years since the lifesaving discovery of insulin (Guest blog) (efpia.eu)

[13] Statins for the primary prevention of cardiovascular disease - PMC (nih.gov)

[14] https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018%2817%2830066-8/fulltext?elsca1=tlpr

[15] Hepatitis C Disease Burden in the United States in the era of oral direct‐acting antivirals - Chhatwal - 2016 - Hepatology - Wiley Online Library

[16] https://www.efpia.eu/media/412939/efpia-economic-societal-footprint-industry-final-report-250619.pdf

[17] Announcing the winners of the 2021 EFPIA Connecting Healthcare Awards

[18] IT’S TIME TO POWER UP HEALTH SYSTEMS (efpia.eu)

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