Estimands from trial planning to publication in medical journals: The ETHOS trial Virtual event
Building on the previous webinar series we will present a refresher on the key elements of the estimand framework and use the ETHOS study to illustrate the estimand framework and to highlight the different options that may be of interest to different stakeholders. The background and disease context of the case will be described, the important events (termed intercurrent events) occurring in the trial will be described and three estimands will be showcased. It will then be explored how best to communicate the estimands in medical journals.
Topics of discussion will be raised at different points during the training and there will be time allowed (30 mins) to answer your questions, which can be posted via the chat. Questions on how estimands should be communicated in medical journals and how to encourage their inclusion in journal articles are particularly encouraged.
Who is this event intended for?
Clinicians, Regulators, Investigators, Academics, members of Ethics Committees, Statisticians, referees and editors of medical journals.
What is the benefit of attending?
Gain alignment on the clinical question(s) of interest; frame clinical questions which may be of interest to different stakeholders; be transparent when communicating trial results.
Paul Dorinsky (AstraZeneca) and David Wright (AstraZeneca)